European Journal of Rheumatology
Invited Review

Relapsing polychondritis


Department of Rheumatology, Koç University Faculty of Medicine, İstanbul, Turkey

Eur J Rheumatol 2015; 2: 155-159
DOI: 10.5152/eurjrheum.2015.0036
Read: 2537 Downloads: 2030 Published: 03 September 2019


Relapsing polychondritis (RPC) is a unique and rarely observed autoimmune condition regarded as recurrent extensive chondritis of the auricular, nasal, and tracheal cartilages. Moreover, heart, main arteries, skin, and eyes may be involved. Several forms of clinical manifestations may be seen, and the pathogenesis still remains anonymous. A concomitant disease, particularly myelodysplasia or other systemic autoimmune disease can be detected in one-third of the patients with RPC. The treatment of RPC should be considered on personal basis and classified according to disease activity and severity. This study reviews the available data on clinical manifestations, pathogenesis, diagnosis, and therapeutics of the RPC.

EISSN 2148-4279