European Journal of Rheumatology
Invited Review

Pre-rheumatoid arthritis and its prevention


Department of Internal Medicine, KMCT Medical College, Kerala, India

Eur J Rheumatol 2017; 4: 161-165
DOI: 10.5152/eurjrheum.2017.16006
Read: 3772 Downloads: 2445 Published: 03 September 2019


Pre-rheumatoid arthritis (pre-RA) is the preclinical period of the disease that precedes the onset of clinically apparent RA. It includes the interaction between genetic and environmental risk factors and development of disease-related autoantibodies and joint symptoms and signs, which may be considered nonspecific or unclassified for RA. A better understanding of the pre-RA stage will be useful in developing screening programs for early detection of RA. Identifying and modifying risk factors such as smoking, periodontitis, obesity, viral infections, and hormonal or dietary factors will be useful in preventing RA in susceptible population.

EISSN 2148-4279