Multiple Scleosis Center, Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Mathilda Mandel
Blood Bank, Sheba Medical Center, Ramat-Gann, Israel
Yehuda Sheonefeld
Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Achiron, A., Mandel, M., & Sheonefeld, Y. (2020). Coronavirus 2019 outbreak pathogenesis: Why China and Italy?. European Journal of Rheumatology, 7(2), S99-S101. https://doi.org/10.5152/eurjrheum.2020.2068
COVID-19 has spread to most countries in the world. However, there are differences in the rate of infection in different countries. Specifically, high incidence was reported in specific areas in China (Wuhan) and Italy (Lombardy). These differences may be related to different Human Leucocyte Antigen (HLA) patterns in various geographic areas. We suggest HLA spreading between Italy and China is related to the travels of Marco Polo through the Silk Road as a potential historic explanation to COVID-19 spreading.
Cite this article as: Achiron A, Mandel M, Sheonefeld Y. Coronavirus 2019 outbreak pathogenesis: Why China and Italy?. Eur J Rheumatol 2020; 7(Suppl 2): S99-S101.
Copyright (c) 2020 European Journal of Rheumatology
Affiliations
Anat Achiron
Multiple Scleosis Center, Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Mathilda Mandel
Blood Bank, Sheba Medical Center, Ramat-Gann, Israel
Yehuda Sheonefeld
Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Cite this Article
Achiron, A., Mandel, M., & Sheonefeld, Y. (2020). Coronavirus 2019 outbreak pathogenesis: Why China and Italy?. European Journal of Rheumatology, 7(2), S99-S101. https://doi.org/10.5152/eurjrheum.2020.2068