Invited Review

Semaphorin3A: A potential therapeutic tool in immune-mediated diseases

Volume 5 · Issue 1 Publish Date: September 3, 2019
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DOI
Zahava Vadasz
Department of Allergy and Clinical Immunology, Bnai-Zion Medical Center, Haifa, Israel
Elias Toubi
Department of Allergy and Clinical Immunology, Bnai-Zion Medical Center, Haifa, Israel
Vadasz, Z., & Toubi, E. (2019). Semaphorin3A: A potential therapeutic tool in immune-mediated diseases. European Journal of Rheumatology, 5(1), 58–61. https://doi.org/10.5152/eurjrheum.2017.17076
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Abstract

Abstract

 

The significance of semaphorin3A (sema3A) in regulating immune-mediated inflammation is widely reported. There are multiple mechanisms involved in the process of sema3A-mediated regulation. One of them is the ability of sema3A to maintain a sufficient regulation of both T-cell and B-cell activation. Because it is involved in the pathogenesis of many autoimmune, infectious, and malignant diseases, sema3A turns to be a promising therapeutic tool to be studied and applied in these diseases.

 

Cite this article as: Vadasz Z, Toubi E. Semaphorin3A: A potential therapeutic tool in immune-mediated disases. Eur J Rheumatol 2018; 5: 58-61.

Article Info
Published In
Journal European Journal of Rheumatology
Volume / Issue Volume 5 · Issue 1
Pages 58-61
History
Published Online September 3, 2019
Affiliations
Zahava Vadasz
Department of Allergy and Clinical Immunology, Bnai-Zion Medical Center, Haifa, Israel
Elias Toubi
Department of Allergy and Clinical Immunology, Bnai-Zion Medical Center, Haifa, Israel
Cite this Article
Vadasz, Z., & Toubi, E. (2019). Semaphorin3A: A potential therapeutic tool in immune-mediated diseases. European Journal of Rheumatology, 5(1), 58–61. https://doi.org/10.5152/eurjrheum.2017.17076
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