ISSN 2147-9720 | E-ISSN 2148-4279
Case Report
Refractory anemia in systemic sclerosis: myelodisplastic syndrome
1 Department of Rheumatology,Adnan Menderes University Faculty of Medicine, Aydın, Turkey  
2 Department of Hematology, Adnan Menderes University Faculty of Medicine, Aydın, Turkey  
Eur J Rheumatol 2015; 2: 120-121
DOI: 10.5152/eurjrheum.2015.0100
Key Words: Systemic sclerosis, malignancy, myelodisplastic syndrome

Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by small vessel vasculopathy, autoantibodies, and skin or visceral organ fibrosis (lung, oesophagus, kidney etc.) as a result of extracellular collagen deposition. The cancer risk is higher in many rheumatic diseases, including SSc. Various defined malignancies may develop in 3%-11% of patients with SSc. These solid tumors are generally observed in the lung, oesophagus, or breast. In addition, an increased risk for hematological cancers were reported in literature. Herein, we describe an interesting case of SSc complicated by myelodisplastic syndrome (MDS). Our aim is to draw attention to developing cancers and the rare occurence of MDS in patients with SSc. 

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