ISSN 2147-9720 | E-ISSN 2148-4279
Case Report
A severe case of systemic lupus erythematosus with increased pressure communicating hydrocephalus
1 Department of Rheumatology, Marmara University, Faculty of Medicine, Istanbul, Turkey  
2 Department of Neurology, Marmara University, Faculty of Medicine, Istanbul, Turkey  
3 Department of Internal Medicine and Critical Care Unit, Marmara University, Faculty of Medicine, Istanbul, Turkey  
4 Department of Nephrology, Marmara University, Faculty of Medicine, Istanbul, Turkey  
Eur J Rheumatol 2015; 2: 76-77
DOI: 10.5152/eurjrheum.2015.0084
Key Words: Hydrocephalus, increased pressure communicating, systemic lupus erythematosus
Abstract

Normal/increased pressure hydrocephaly is an unusual manifestation of systemic lupus erythematosus (SLE), and the pathogenesis is still unclear. We report the case of an 18-year-old white female with severe refractory renal and pulmonary involvement who developed stupor during intensive immunosuppressive treatment. Enlarged ventricles on imaging and increased intracranial pressure with the exclusion of infectious and hemorrhagic/thrombotic processes suggested increased pressure communicating hydrocephalus associated with SLE. Few case reports are reviewed, and potential pathophysiologic mechanisms are discussed.

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