ISSN 2147-9720 | E-ISSN 2148-4279
Familial Mediterranean fever: An updated review
1 Department of Internal Medicine, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey  
2 Department of Internal Medicine, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey  
Eur J Rheumatol 2014; 1: 21-33
DOI: 10.5152/eurjrheum.2014.006
Key Words: Familial Mediterranean fever, review, aetiology, amyloidosis, treatment

Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder characterised by acute attacks of fever and serosal inflammation. FMF primarily affects Jewish, Armenian, Turkish, and Arab populations. The disease is accompanied by a marked decrease in quality of life due to the effects of attacks and subclinical inflammation in the attack-free periods. Untreated or inadequately treated patients run the risk of amyloidosis, which is an important cause of morbidity and mortality. In this review, the current information available on FMF is summarised.



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