Translation and Psychometric Evaluation of the Profile of Fatigue and Discomfort—Sicca Symptoms Inventory (Short Form) for Patients with Primary Sjögren’s Syndrome: Validity and Reliability Analysis of the Turkish Version

Background: The study aimed to translate the Profile of Fatigue and Discomfort—Sicca Symptoms Inventory Short Form questionnaire into the Turkish language (PROFAD-SSI-SF-T) and to investigate its psychometric properties.

Methods: The study was completed by 104 patients with primary Sjögren’s syndrome (pSS), and 83 patients filled out the scale a second time after 7 days for the retest measurement. The PROFAD-SSISF-T, Functional Assessment Chronic Illness Therapy (Fatigue) (FACIT-F), EULAR Sjögren’s Syndrome Patient Reported Index (ESSPRI), European Quality of Life 5 Dimensions (EQ-5D), and Patient Global Assessment (PaGA) were applied to 104 patients with pSS for convergent validity.

Results: PROFAD-SSI-SF-T found excellent internal consistency (Cronbach’s α=0.935) and high test– retest reliability (ICC: 0.83; 95% CI: 0.75-0.88). The standard error of measurement ranged from 1.01 to 3.52, and the minimum detectable difference ranged from 0.92 to 1.17. There was a range from low to high correlation between the PROFAD-SSI-SF-T with ESSPRI, FACIT-F, and EQ-5D. There were no floor and ceiling effects in the PROFAD-SSI-SF-T scale.

Conclusion: The PROFAD-SSI-SF-T is a valid and reliable scale to evaluate fatigue, discomfort, and sicca symptoms in Turkish patients with primary Sjögren’s syndrome.

Cite this article as: Sari F, Bayram S, Gülsün Pala G, Oskay D, Tufan A. Translation and Psychometric evaluation of the Profile of Fatigue and Discomfort—Sicca Symptoms Inventory (Short Form) for Patients with Primary Sjögren’s Syndrome: Validity and Reliability Analysis of the Turkish Version. Eur J Rheumatol. Published online May 30, 2024. doi: 10.5152/eurjrheum.2024.24009