European Journal of Rheumatology
Case Report

Successful treatment of Acrodermatitis continua of Hallopeau associated with psoriatic arthritis with adalimumab


Department of Medicine, University of Algiers 1, Algiers, Algeria


Department of Medicine, Hadj Lakhdar University, Batna, Algeria

Eur J Rheumatol 2015; 2: 78-79
DOI: 10.5152/eurjrheum.2015.0072
Read: 623 Downloads: 228 Published: 03 September 2019


Acrodermatitis continua of Hallopeau (ACH) is a rare form of pustular psoriasis, mainly affecting distal phalanges of hands and feet. Many therapeutic options exist; however, it tends to be resistant to treatment. We report a 26-year-old man presented with a very severe psoriatic arthritis associated with ACH. Although this patient was resistant to a first line treatment (glucocorticoids and methotrexate), a rapid and dramatic improvement was observed after adalimumab was introduced. The effectiveness and tolerance of the treatment were maintained during the 12-month period of follow-up. This is the first report of the efficacy of adalimumab on ACH in a patient presented with psoriatic arthropathy. 

ISSN 2147-9720 EISSN 2148-4279