European Journal of Rheumatology
Case Report

Recurring posterior reversible encephalopathy syndrome in a patient with polymyositis/systemic sclerosis overlap syndrome triggered by scleroderma renal crisis

1.

Department of General Internal Medicine, Akashi Medical Center, Akashi, Japan

Eur J Rheumatol 2019; 6: 158-160
DOI: 10.5152/eurjrheum.2019.18137
Read: 130 Downloads: 21 Published: 03 September 2019

Abstract

 

In posterior reversible encephalopathy syndrome (PRES) triggered by scleroderma renal crisis (SRC), modulation and adherence in immunosuppressive therapy are key for avoiding recurrence, complications, and death. A patient with polymyositis (PM)/systemic sclerosis (SSc) overlap syndrome developed PRES triggered by SRC. To our knowledge, this is the first report of a case with PRES associated with PM/SSc overlap syndrome. This manifested as altered mental status and headaches. Vasogenic edema was seen by magnetic resonance imaging in the brainstem and cerebral white matter. Antihypertension therapy resulted in improvement in both neurological symptoms and blood pressure (BP). Reversible clinical course and radiological change were consistent with PRES diagnosis. Here, the importance of BP maintenance and removal of precipitating factors of PRES is shown.

 

 

Cite this article as: Kobatake M, Ishimaru N, Kanzawa Y, Seto H, Kinami S. Recurring posterior reversible encephalopathy syndrome in a patient with polymyositis/systemic sclerosis overlap syndrome triggered by scleroderma renal crisis. Eur J Rheumatol 2019; 6(3): 158-60.

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ISSN2147-9720 EISSN 2148-4279