European Journal of Rheumatology
Case-Based Review

Granulomatosis with polyangiitis: The trigger cannot be long hidden


Department of Medicine, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA


Department of Medicine and Surgery, Tufts University School of Medicine, Boston, Massachusetts, USA


Division of Pulmonary & Critical Care and Sleep Medicine, Tufts Medical Center, Boston, Massachusetts, USA

Eur J Rheumatol 2022; 9: 54-57
DOI: 10.5152/eurjrheum.2021.21093
Read: 1342 Downloads: 650 Published: 01 January 2022

Granulomatosis with polyangiitis, or GPA, is a form of vasculitis that affects multiple organs especially the respiratory tract and the kidneys. The diagnosis is suspected with the clinical presentation and elevated serum titer of antineutrophil cytoplasmic antibodies and confirmed with the biopsy of the affected organ. Viral infection has been described as one of the triggers of the immune system in developing GPA. In this report, we describe a rare case of GPA that developed following cytomegalovirus infection in a patient with unknown immunocompromised medical condition.
Cite this article as: Gayen S, Zhang D, Sternlicht E, Bulanowski D, Tabba M. Granulomatosis with polyangiitis: the trigger cannot be long hidden. Eur J Rheumatol. 2021;9(1):54-57.

EISSN 2148-4279