European Journal of Rheumatology

Familial Mediterranean fever: An updated review


Department of Internal Medicine, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey


Department of Internal Medicine, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey

Eur J Rheumatol 2014; 1: 21-33
DOI: 10.5152/eurjrheum.2014.006
Read: 713 Downloads: 370 Published: 03 September 2019


Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder characterised by acute attacks of fever and serosal inflammation. FMF primarily affects Jewish, Armenian, Turkish, and Arab populations. The disease is accompanied by a marked decrease in quality of life due to the effects of attacks and subclinical inflammation in the attack-free periods. Untreated or inadequately treated patients run the risk of amyloidosis, which is an important cause of morbidity and mortality. In this review, the current information available on FMF is summarised.



ISSN2147-9720 EISSN 2148-4279