European Journal of Rheumatology
Original Article

ABO blood groups and rheumatic diseases


Department of Immunology-Rheumatology, Adnan Menderes University School of Medicine, Aydın, Turkey

Eur J Rheumatol 2017; 4: 250-253
DOI: 10.5152/eurjrheum.2017.17044
Read: 3124 Downloads: 1306 Published: 03 September 2019


Objective: Various genetic and environmental risk factors have been shown to be associated with the incidence of rheumatic diseases. However, the pathogenesis of rheumatic diseases poorly understood. Several studies have shown associations of ABO blood groups with various diseases. Our study aimed to determine whether there is an association between the types of rheumatic diseases and ABO and Rh blood groups.


Material and Methods: The study included the patients, followed up at the Immunology-Rheumatology clinic between January 2016 and December 2016 for diagnosis of rheumatic disease, who had an ABO Rh blood data. Age, gender, type of rheumatic disease, ABO Rh blood groups were recorded.


Results: When 823 patients were assessed for blood types, 42.5% patients had A type, 33.2% had O type, 15.4% had B type, and 8.9% had AB type. There was significant difference in the distribution of blood types in rheumatic diseases. While SpA, vasculitis, UCTD, Behçet’s and RA were more common in the patients with A blood type; FMF, SLE, SSc and SjS were more common in the patients with O blood type. In addition, the blood type where all the diseases are observed the least commonly was AB. There was significant difference in the distribution of Rh factor in rheumatic diseases. 92.2% patients were Rh positive and 7.8% patients were Rh negative.



Conclusion: In our study, we thought that the higher incidence of different rheumatic diseases in different blood types was associated with different genetic predisposition.


Cite this article as: Çildağ S, Kara Y, Şentürk T. ABO blood groups and rheumatic diseases. Eur J Rheumatol 2017; 4: 250-3.

EISSN 2148-4279