ISSN 2147-9720 | E-ISSN 2148-4279
Case Report
Muscle weakness as a presenting symptom in ANCA-associated vasculitis
1 Department of Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan  
2 Department of Neurology, National Hospital Organization Kure Medical Center/Chugoku Cancer Center, Japan  
Eur J Rheumatol 2018; 5: 139-141
DOI: 10.5152/eurjrheum.2017.17067
Key Words: anti-neutrophil cytoplasmic antibody, ANCA-associated vasculitis, muscle weakness, muscle biopsy, granulomatosis with polyangiitis
Abstract

 

Muscle weakness is rarely a presenting symptom of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), although the disease frequently involves the lungs, skin, neurons, and kidneys. Here we describe a case of AAV presenting with muscle weakness in which only muscle biopsy could confirm the diagnosis. The literature review, including three similar cases, suggested that patients with ANCA-associated muscle vasculitis likely had myalgia, normal levels of creatine kinase, pulmonary fibrosis, rheumatoid factor, and muscle edema on MRI.


Cite this article as: Oiwa H, Kurashige T. Muscle weakness as a presenting symptom in ANCA-associated vasculitis. Eur J Rheumatol 2018; 5: 139-41.

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