ISSN 2147-9720 | E-ISSN 2148-4279
1 Department of Rheumatology, Medical Park Gaziantep Hospital, Gaziantep, Turkey  
2 Department of Rheumatology, Mersin University School of Medicine, Mersin, Turkey  
3 Department of Rheumatology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey  
4 Private Practice, Gaziantep, Turkey  
Eur J Rheumatol ; : -


Granulomatosis with polyangiitis (GPA) is a primary systemic vasculitis characterized by granulomatous inflammation. Arthritis in GPA is most commonly associated with large joints, particularly the knees and ankles; however, symmetrical polyarthritis of small joints has been rarely reported in literature. Here, we describe retrospective analysis of six patients with GPA showing initial symptom of symmetrical polyarthritis who were followed-up by three different rheumatology departments. Male sex, anti-cyclic citrulinated peptide negativity, and early arthritis period are important clues for GPA.


Cite this article as: Kısacık B, Önder ME, Sayarlıoğlu M, Onat AM. Symmetric polyarthritis as an initial symptom in granulomatosis with polyangiitis: A report of six cases and review of the literature. Eur J Rheumatol 2018; DOI: 10.5152/eurjrheum.2018.17050

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