Anakinra use during pregnancy: Report of a case with Familial Mediterranean Fever and infertility
Department of Internal Medicine, Ankara University School of Medicine, İbn-i Sina Hospital, Ankara, Turkey
Department of Rheumatology, Yıldırım Beyazıt University Medical School, Atatürk Research and Training Hospital, Ankara, Turkey
Eur J Rheumatol 2017; 4: 66-67
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Key Words: Anakinra, Familial Mediterranean Fever, interleukin-1β, pregnancy
Familial Mediterranean fever (FMF), affecting people of Mediterranean origin, is an endemic and sometimes problematic disease because of colchicine resistance/intolerance, with relative lack of treatment alternatives, and disease- or treatment-related issues, such as subfertility. Anakinra, being a rational and effective treatment alternative, has no conclusive human pregnancy data. Here we report a case of FMF with infertility who became pregnant with in vitro fertilization (IVF) under treatment with anakinra, along with the pregnancy outcome.