ISSN 2147-9720 | E-ISSN 2148-4279
Case Report
Successful treatment of Acrodermatitis continua of Hallopeau associated with psoriatic arthritis with adalimumab
1 Department of Medicine, University of Algiers 1, Algiers, Algeria  
2 Department of Medicine, Hadj Lakhdar University, Batna, Algeria  
Eur J Rheumatol 2015; 2: 78-79
DOI: 10.5152/eurjrheum.2015.0072
Key Words: Acrodermatitis continua of Hallopeau, psoriatic arthritis, adalimumab

Acrodermatitis continua of Hallopeau (ACH) is a rare form of pustular psoriasis, mainly affecting distal phalanges of hands and feet. Many therapeutic options exist; however, it tends to be resistant to treatment. We report a 26-year-old man presented with a very severe psoriatic arthritis associated with ACH. Although this patient was resistant to a first line treatment (glucocorticoids and methotrexate), a rapid and dramatic improvement was observed after adalimumab was introduced. The effectiveness and tolerance of the treatment were maintained during the 12-month period of follow-up. This is the first report of the efficacy of adalimumab on ACH in a patient presented with psoriatic arthropathy. 

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