ISSN 2147-9720 | E-ISSN 2148-4279
Case Report
Positive anti-MOG antibodies in a patient with Sjögren's syndrome and transverse myelitis
1 Department of Rheumatology, Clinical Research Facility, Royal Victoria Infirmary, Newcastle upon Tyne, UK  
2 Department of Rheumatology, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK  
Eur J Rheumatol ; : -
DOI: 10.5152/eurjrheum.2018.18041
Key Words: Transvere myelitis, primary Sjögren’s syndrome, neuromyelitis optica spectrum disorder, neurological manifestations, myelin-oligodendrocyte glycoprotein, antibodies
Abstract

Twenty percent of patients with Sjögren’s syndrome experience associated neurological disease. Transverse myelitis (TM) frequently forms part of a neuromyelitis optica spectrum disorder associated with the presence of anti-aquaporin 4 (AQP4) antibodies. We report the first described case of a patient who developed TM and the presence of a newly recognized antibody, anti-myelin oligodendrocyte protein (MOG), who went on to develop Sjögren’s syndrome. AQP4 and MOG antibodies should be tested to guide prognostically the chances of further relapse as well as the type and duration of immunotherapy in patients with coexisting Sjögren's syndrome and TM.


Cite this article as
: Jobling K, Ledingham D, Ng WF, Guadagno J. Positive anti-MOG antibodies in a patient with Sjögren's syndrome and transverse myelitis. Eur J Rheumatol DOI: 10.5152/eurjrheum.2018.18041

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