ISSN 2147-9720 | E-ISSN 2148-4279
Case Report
Microscopic polyangiitis with dermatomyositis
1 Department of Rheumatology, University of California, David Geffen School of Medicine, Los Angeles, California, USA; U.S. Department of Veterans Affairs, Los Angeles, California, USA  
2 Department of Rheumatology, University of California, David Geffen School of Medicine, Los Angeles, California, USA.  
Eur J Rheumatol ; : -
DOI: 10.5152/eurjrheum.2017.17008
This article was viewed 207 times, downloaded 65 times

Key Words: Dermatomyositis, microscopic polyangiitis, ANCA associated vasculitis, renal failure
Abstract

Dermatomyositis is a rare autoimmune disease with a heterogeneous presentation that often has multiple extramuscular manifestations, although it does not typically involve the renal function. A 62-year-old female presented with proximal muscle weakness and rashes, which are classic symptoms of dermatomyositis without creatine kinase (CK) elevation. Initial serologic evaluation revealed a positive p-ANCA, although she did not develop renal failure for several months, at which point renal biopsy findings were consistent with microscopic polyangiitis. The patient was initially treated with cyclophosphamide, maintained with rituximab, and has been in remission for more than 2 years. Dermatomyositis and microscopic polyangiitis are both uncommon diseases, but are concomitantly present in this patient. A positive p-ANCA and development of renal insufficiency should be promptly evaluated in dermatomyositis patients.

 

Cite this article as: Bauer EM, Brahn E. Microscopic polyangiitis with dermatomyositis. Eur J Rheumatol 2017; 4: DOI: 10.5152/eurjrheum.2017.17008.

Key Words
Authors
All
Author’s Corner
Survey
AVES | Copyright © 2017 Medical Research and Education Association | Latest Update: 15.09.2017